Otodus aksuaticus was a large predatory otodontid shark belonging to the lineage that would later produce the giant megatooth sharks. Early otodontids were already powerful marine predators, and their robust teeth show that this ecological role was established well before the enormous later members of the group evolved.

Its broad, thick teeth combined a strong central cutting crown with lateral cusplets. This dentition was suited to seizing and cutting substantial prey, making fishes and other sizeable marine vertebrates plausible food items.

The species is known predominantly from teeth, so its body size and hunting behaviour should not be reconstructed too precisely. What the fossils do show is a heavily built feeding apparatus belonging to one of the major macropredatory shark lineages of the Palaeogene.