Abdounia minutissima was a very small requiem-shark relative and one of the more diminutive predatory sharks represented in early Eocene deposits. It belonged to an early carcharhinid radiation long before modern requiem sharks became such a prominent part of marine ecosystems.

Its minute pointed teeth were adapted for grasping small prey. A diet of small fishes, crustaceans and other invertebrates is plausible from the dentition and from comparison with small living carcharhiniform sharks, although direct evidence of its prey is not preserved.

The species is known almost entirely from isolated teeth, so its overall body size and appearance cannot be reconstructed with precision. Even so, it provides evidence that the London Clay shark fauna included small predators occupying ecological roles very different from the large lamniform and cow sharks living alongside them.